Which medication is NOT classified as an SSRI?

Cymbalta is not classified as an SSRI (Selective Serotonin Reuptake Inhibitor). Instead, it is a serotonin-norepinephrine reuptake inhibitor (SNRI), which means it works by affecting both serotonin and norepinephrine levels in the brain. This distinction is important because SNRIs are used in the management of depression and anxiety disorders, similar to SSRIs, but they may have different effects and side effects due to their dual-action mechanism.

In contrast, Celexa (citalopram), Lexapro (escitalopram), and Zoloft (sertraline) are all classified as SSRIs. SSRIs primarily increase the level of serotonin in the synaptic cleft by inhibiting its reuptake into the presynaptic cell, thereby enhancing mood and alleviating symptoms of depression. Understanding these classifications helps in recognizing the different therapeutic profiles and potential side effects of medications used in treating mental health conditions.